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Pancreas

Pancreas

The pancreas is a yellowish fleshy organ that is about 6- 8 inches long. It is placed horizontally across the upper abdomen, behind the stomach. About 95% of the pancreas is made up of the exocrine gland (which secretes digestive enzymes) and nearly 5 % of it is made up of endocrine glands (which secretes hormones like insulin). The exocrine glands secrete digestive enzymes, which helps to break down carbohydrates, fats, proteins, and acids. An ideal, healthy pancreas will secrete about 1 liter of these enzymes daily. The endocrine gland secretes hormones such as insulin and glucagon into the bloodstream to regulate the blood sugar level.

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Pancreatitis

The inflammation of the pancreas is called pancreatitis and it is a condition that occurs when the digestive enzymes in the pancreas start digesting itself. The condition can either be acute- when the disease manifests suddenly or chronic- when the disease manifests over the years. Both conditions can cause very serious health issues.

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Periampullary cancers

The ampulla of Vater comprises the junction of the biliary and pancreatic ducts and is surrounded by the sphincter of Oddi which is a 1cm long smooth muscle structure. The distal constricted end of the ampulla opens into the posteromedial aspect of the duodenum (proximal part of the small intestine) which is called papilla.

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Periampullary tumors

The ampulla of Vater comprises the junction of the biliary and pancreatic ducts and is surrounded by the sphincter of Oddi which is a 1cm long smooth muscle structure. The distal constricted end of the ampulla opens into the posteromedial aspect of the duodenum (proximal part of the small intestine) which is called papilla.

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Pancreatic Cancers

When there is exponential growth, division and spread of the cells in the tissues of the pancreas, the condition is termed as pancreatic cancer. Adenocarcinoma is the commonest type. These are aggressive tumors with poor outcome. Though it is unclear as to how certain people get pancreatic cancer, factors that contribute to it are smoking, obesity, genetic factors, and chronic pancreatitis.

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